Reduced and Thinned Elastic Fibers in Skin Tag

Increased dermal elastic fibers in the tight skin mouse.

OBJECTIVE The tight skin (Tsk-1) mouse has been proposed as a model for systemic sclerosis on the basis of increased accumulation of collagen and glycosaminoglycans in the skin, and by the presence of serum autoantibodies. The genetic basis of the mutation has been identified as a genomic duplication within the fibrillin-1 (Fbn-1) gene that results in a larger than normal Fbn-1 transcript, but ...

Elastic Fibers in Flows

Frequency of Diabetes Mellitus in Skin Tag Patients in Comparison with Control Group

Background & Aims: Diabetes mellitus is one of the most common types of chronic disease leading to serious complications such as blindness, end stage renal disease (ESRD), neuropathy and cardiac disorders. Skin tag is a common benign skin tumor that its association with impaired carbohydrate metabolism has been reported in some studies. The aim of this study was to compare the frequency of diab...

A Case Report of a Giant Skin Tag

Skin tags are skin-colored, asymptomatic, pedunculated lesions located at the neck, axillae or groin. It affects any age, including infants. We report a 60-year-old Iranian woman with a giant pedunculated skin tag on the left thigh for 10 years. It measured 10 cm in length and 7 cm in width, distally.

An elastic second skin.

We report the synthesis and application of an elastic, wearable crosslinked polymer layer (XPL) that mimics the properties of normal, youthful skin. XPL is made of a tunable polysiloxane-based material that can be engineered with specific elasticity, contractility, adhesion, tensile strength and occlusivity. XPL can be topically applied, rapidly curing at the skin interface without the need for...